Ab negative blood9/7/2023 ![]() ![]() On the surface of every one of our red blood cells, we have up to 342 antigens-molecules capable of triggering the production of specialized proteins called antibodies. It would be straightforward if we all had the same blood. Hence the hundreds of millions of people flowing through blood-donation centers across the world, and the thousands of vehicles transporting bags of blood to processing centers and hospitals. If we lose a lot of blood in surgery or an accident, we need more of it-fast. Red blood cells carry oxygen to all the cells and tissues in our body. In 50 years, researchers have turned up only 40 or so other people on the planet with the same precious, lifesaving blood in their veins. Very few people in the world knew his blood type did-could-exist. Surely it was impossible for this man seated beside her to be alive, let alone apparently healthy? ![]() But when she read the details closely, her eyes widened. The nurse in Annemasse, France, could tell from the label on the blood bag destined for Paris that this blood was pretty unusual. It was quicker that way: If the man donated in Switzerland, his blood would be delayed while paperwork was filled out and authorizations sought. Because of this timing, the first pregnancy is not affected: it is in subsequent pregnancies that the antibodies in the mother’s body can destroy the baby’s red blood cells.His doctor drove him over the border. ![]() This occurs because a few of the baby's red cells cross the placenta into the mother's circulation, particularly during labor. If a baby is positive and the mother is negative, she may make anti-Rh in response to the baby’s blood. Problems with the Rh factor also occur during pregnancy. Rh negative persons don't automatically make anti-Rh, but if they receive Rh-positive blood, most will then make the antibody that will destroy Rh-positive red cells if they are transfused a second time. If he receives blood from someone with B or AB blood his anti-B will destroy the transfused red cells, a serious reaction that, in the worst case, can lead to death. Thus, someone with blood type A does not have the B group on his red cells, and always makes an antibody against B. Approximately 85% of the population is Rh positive.īlood typing prevents transfusion reactions which are caused by blood group antibodies. Thus every person is either Rh positive or Rh negative while also belonging to one of the ABO groups. Those who lack the factor are called Rh negative. Those who have this "Rhesus" factor on their red blood cells are considered Rh positive. A person can have one or the other (types A or B respectively), both (type AB), or neither (type O).Ī blood protein which was discovered in 1940. He received the Nobel prize for the discovery, which eventually changed transfusion from a desperate measure to a routine medical intervention.Ī person's ABO type is determined by the presence or absence of the A or B substance on his red cells. The ABO blood types were discovered by Landsteiner around 1900. This creates a total of eight main blood types. Within the ABO system, people can be one of four groups: O, A, B, or AB with respect to Rh a person is either positive or negative. ![]() The two most important ways of classifying blood in transfusion work are a person's ABO and Rh groups. There are over 600 different blood groups, but only a few of them are important for routine transfusions. Related blood groups are organized into 'blood group systems'. This may cause the donor red blood cells to be destroyed in a 'transfusion reaction'. Complex chemical substances found on the surface of red cells are different for each blood group. When donor red blood cells carrying a certain blood group are transfused into a recipient who lacks that group, the recipient may make an antibody that binds to or 'labels' that blood group or 'blood group antigen' as foreign. Blood types or groups are differences between people's blood that can be recognized by the immune system. ![]()
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